Expression of the Irisin Precursor FNDC5 in Skeletal Muscle Correlates With Aerobic Exercise Performance in Patients With Heart Failure
نویسندگان
چکیده
منابع مشابه
Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure.
BACKGROUND Exercise-induced increase in peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) expression has been shown to increase the expression of the fibronectin type III domain containing 5 (FNDC5) gene and thereby its product, irisin, in mice. Given that exercise intolerance is a hallmark characteristic of heart failure (HF), and because PGC-1α and irisin promote exercise b...
متن کاملEffects of Aerobic and Resistance Exercise Program on Physical Adaptation in the Elderly Men Patients with Heart Failure
Introduction: Diminished physiological tolerance induced heart failure among the elderly patients limit doing their daily activities. Exercising as a non-medical intervention is not usually mentioned for daily activities promotion. The current study was conducted aiming to explore the effects of aerobic and resistance exercise program on physical adaptation in the elderly men patients with hear...
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چکیده ندارد.
Skeletal muscle mass and exercise performance in stable ambulatory patients with heart failure.
The purpose of this study was to determine whether skeletal muscle atrophy limits the maximal exercise capacity of stable ambulatory patients with heart failure. Body composition and maximal exercise capacity were measured in 100 stable ambulatory patients with heart failure. Body composition was assessed by using dual-energy X-ray absorption. Peak exercise oxygen consumption (VO2peak) and the ...
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ژورنال
عنوان ژورنال: Circulation: Heart Failure
سال: 2012
ISSN: 1941-3289,1941-3297
DOI: 10.1161/circheartfailure.112.969543